Dry spells in intimacy are more common than you might think—stress, busy schedules, health changes, or shifting priorities can quietly push sex to the back burner for weeks, months, or even longer. At first it may feel like no big deal, but over time you might start noticing subtle shifts in mood, energy, sleep, or even physical function that leave you wondering if something deeper is going on. The truth is, while many people thrive without regular sex, research suggests that prolonged abstinence can quietly reduce some of the natural health boosts intimacy provides. And one area in particular—something both men and women experience—stands out as the most noticeable change of all. Keep reading to discover exactly what science says.
Why Sexual Activity Matters for Overall Wellness

Intimacy does more than strengthen emotional bonds. It triggers a cascade of hormones—oxytocin (the “bonding hormone”), endorphins (natural painkillers), and dopamine (the reward chemical)—that support mood stability, stress relief, and even immune function.

Studies consistently link moderate sexual frequency (whatever feels right for you) to benefits like better heart health, deeper sleep, and lower inflammation markers. That doesn’t mean abstinence is harmful for everyone—far from it. Age, overall health, relationship status, and personal values all play major roles. But for those who notice changes during long dry spells, understanding the science can help you decide what steps to take next.
5 Ways Prolonged Abstinence Might Affect Your Body

Research on this topic comes mostly from observational studies and smaller clinical trials. Results vary widely, but here are five areas where differences often appear.
5. Stress and Mood Can Feel Harder to Manage