3. Certain Antibiotics (Aminoglycosides like Gentamicin, Vancomycin)
Some antibiotics are directly toxic to kidney tubules—the structures responsible for filtering and reabsorbing substances.
Aminoglycosides and vancomycin are well-documented examples, especially when used in hospital settings or for serious infections.
Medical guidelines emphasize careful dosing and monitoring of kidney function during treatment.
4. ACE Inhibitors and ARBs (Lisinopril, Losartan, etc.)
These blood pressure medications are excellent for heart and kidney protection in many patients.
However, in certain situations—such as dehydration, low blood volume, or underlying kidney artery narrowing—they can cause a sudden drop in kidney filtration rate.
Doctors routinely monitor kidney function when starting or adjusting these drugs.
5. Radiocontrast Dyes Used in CT Scans and Angiograms
Iodinated contrast agents help make blood vessels and organs visible on imaging.
In people with reduced kidney function, diabetes, or dehydration, these dyes can trigger contrast-induced nephropathy—a potentially reversible but serious form of acute kidney injury.
Pre-scan hydration and screening are standard preventive measures in hospitals.
6. Diuretics (“Water Pills”)
Diuretics help remove excess fluid and control blood pressure.
When overused or combined with dehydration, they can reduce blood volume too much, stressing the kidneys.
Close medical supervision and regular electrolyte checks help avoid complications.
7. Lithium (Used for Bipolar Disorder)
Lithium has been a cornerstone treatment for mood stabilization for decades.
Long-term use can lead to chronic kidney changes, including reduced concentrating ability and, in some cases, progressive damage.
Regular blood tests and kidney monitoring are essential for anyone on lithium therapy.
