Short-term, occasional use is generally low-risk for most, but frequent or prolonged reliance warrants caution. Nasal saline sprays or steroid nasal sprays often provide relief without the same systemic effects.
2. Tricyclic Antidepressants
Older antidepressants like amitriptyline are sometimes prescribed for chronic pain, neuropathy, or depression.
They can affect the heart’s electrical activity, potentially prolonging the QT interval and increasing arrhythmia risk—especially at higher doses or in those with preexisting heart conditions. Newer antidepressants (SSRIs or SNRIs) typically carry fewer cardiac concerns.
If you’re taking one for pain or mood, your doctor may consider monitoring or switching to alternatives with better cardiovascular profiles.
1. Calcium Supplements
Many adults over 60 take calcium pills to support bone health and prevent osteoporosis.
Some studies have raised questions about high-dose supplements contributing to arterial calcification, potentially increasing cardiovascular risk slightly compared to calcium obtained from food. A 2016 meta-analysis in the Journal of the American Heart Association noted mixed but concerning findings.
Experts generally recommend getting calcium primarily from dietary sources—dairy, leafy greens, fortified foods—and using supplements only when diet falls short, under medical guidance.
Quick Comparison of the Five Categories
Medication Category Main Potential Concern Common Safer Considerations
NSAIDs Fluid retention, higher blood pressure Acetaminophen, topical versions, physical therapy
PPIs Nutrient deficiencies, possible CV events Short-term use, lifestyle changes for reflux
Oral Decongestants Blood pressure spikes Nasal sprays, saline rinses
Tricyclic Antidepressants Electrical rhythm changes Newer antidepressant classes
Calcium Supplements Possible arterial calcification Calcium-rich foods first
Practical Steps to Take Right Now
Make a complete list of every medication and supplement you take, including doses and how long you’ve used them.
Schedule a medication review with your doctor or pharmacist—many offer dedicated appointments for this.
Ask specifically: “Does any of my current regimen carry cardiovascular warnings for someone my age?”
Discuss alternatives, dose adjustments, or monitoring tests (blood pressure, electrolytes, ECG if relevant).
Track symptoms like swelling, irregular heartbeat, or unusual fatigue and report them promptly.
These conversations often lead to simpler, safer regimens without sacrificing relief or protection.
Final Thoughts
Knowledge about these five common medication categories doesn’t mean stopping them abruptly—it means having informed discussions with your healthcare provider. Small adjustments can often preserve benefits while reducing potential risks.
You now have clear, evidence-based insights into medications that research has flagged for possible heart concerns after age 60. Taking that list to your next appointment is one of the most proactive steps you can take for long-term heart health.
Frequently Asked Questions
1. Can I just stop taking these medications on my own?
No—sudden stops can cause rebound issues or withdrawal effects. Always consult your doctor before making changes.
2. Are these risks the same for everyone over 60?
No. Individual factors like existing heart conditions, other medications, and overall health play a big role. Personalized advice is essential.
3. Is it safe to use any over-the-counter pain reliever after 60?
Many people use them safely occasionally, but regular use of NSAIDs warrants a discussion with your provider about heart risks.
